Infigratinib靶向的FGFR3（成纤维细胞生长因子受体3）正是驱动ACH疾病发生的关键靶点，2月12日，BridgeBio公布Infigratinib在ACH中取得的首个具有统计学显著改善意义的3期顶线结果，公司计划下半年向FDA提交新药申请。
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At the OpenAI all-hands, staff were told that the most challenging aspect of the deal for leadership was concern over foreign surveillance, and that there was a major worry about AI-driven surveillance threatening democracy, according to the source. However, company leaders also seemed to acknowledge the reality that governments will spy on adversaries internationally, recognizing claims that national security officers “can’t do their jobs” without international surveillance capabilities. References were made to threat intelligence reports showing that China was already using AI models to target dissidents overseas.